Here is a quick overview of the 4 primary Growth Hormone Releasing Peptides most commonly used i athleti pursuits today. This is meant as a means to determine what might be the best and most appropriate application for your individual research needs.
Hexarelin is in the category of drugs known as GH secretagogues. This category of drugs includes GHRP-2, GHRP-6, Ipamorelin, and Hexarelin. Its primary function is to stimulate the pituitary gland to produce more growth hormone. Like the other GHRPs, it has a 2-fold mechanism of action, in that it causes an increase in GH through amplifying the natural growth hormone releasing hormone (GHRH) signal transduction pathway, as well as by suppressing the actions of Somatostatin.
IGF stands for insulin-like growth factor. It is a natural substance that is produced in the human body and is at its highest natural levels during puberty. During puberty IGF is the most responsible for the natural muscle growth that occurs during these few years. There are many different things that IGF does in the human body; I will only mention the points that would be important for physical enhancement. Among the effects the most positive are increased amino acid transport to cells, increased glucose transport, increased protein synthesis, decreased protein degradation, and increased RNA synthesis.
For decades BB’rs have been using HCG both on-cycle and off-cycle to prevent testicular atrophy, as well as help re-grow the testes prior to commencing PCT. HCG, known as Human Chorionic Gonadotropin, accomplishes this function by mimicking the actions of LH (leutinizing hormone) within the body, which is the hormone responsible for stimulating testosterone production. Aside from the obvious cosmetic benefits associated with testicular maintenance, retaining function of the testes helps set the stage for a more rapid post-cycle recovery by retaining the organ’s ability to respond optimally to circulating LH.
Growth Hormone Releasing Peptide (GHRP-2) is a synthetic ghrelin analogue. Like ghrelin, it stimulates release of endogenous growth hormone from somatotropes in the anterior pituitary; also like ghrelin, it is synergistic with endogenous growth hormone releasing-hormone (GHRH) as well as with synthetic GHRH analogues such as Sermorelin or GRF(1-29). Whereas GHRP-2 and other ghrelin analogues increase the number of somatotropes involved in the GH pulse by inhibiting somatostatin, GHRH increases the pulse amplitude per pituitary cell or somatotrope by other means. Unlike ghrelin, GHRP is not lipogenic meaning it does not induce fat storage. While ghrelin has a very important role in hunger, GHRP-2 as an analog of ghrelin does not increase appetite significantly.
DAC conjugated CJC 1295 is an hGH secretogue that is unique by way of an additional lysine molecule that is added to facilitate the DAC complex. This conjugation makes for a much longer half-life. CJC 1295 DAC is a exceptionally designed peptide and is known for being the finest of the hGH secretogues.
Medical testing has shown that Cialis is effective in 60%-80% of cases when used to treat erectile dysfunction in subjects. Most failure cases are from subjects that have had some form of surgery that made getting or maintaining an erection physically impossible. Tadalafil produces results similar to Viagra, but the effects of Tadalafil last longer than Viagra. In addition, Tadalafil can be taken on an empty stomach or with a meal. When Tadalafil and Viagra were compared in a study Tadalafil allowed for more sexual frequency and that in turn raised Testosterone levels higher in the Cialis group.
A drug approved in Europe to treat osteoporosis has now been shown to stop the growth of breast cancer cells, even in cancers that have become resistant to current targeted therapies, according to a Duke Cancer Institute study.
The findings, presented June 15, 2013, at the annual Endocrine Society meeting in San Francisco, indicate that the drug bazedoxifene packs a powerful one-two punch that not only prevents estrogen from fueling breast cancer cell growth, but also flags the estrogen receptor for destruction.
Alexander Fleming's accidental discovery of penicillin was one of the most important—and fortunate—mistakes of the 20th century. Nearly 100 years later, James Bradner thinks he and his colleagues may have stumbled on something that could be similarly world-changing: A molecule that could lead to the world's first effective male birth control pill, which could be ready for human testing within a year.