In every male body a certain ratio of the hormones testosterone to epitestosterone are produced on a daily basis. In a typical male, this ratio rarely goes over 4 parts testosterone to 1 part epitestosterone. Therefore, if an athlete were to inject exogenous testosterone into the body, testosterone levels would increase, but epitestosterone would not. This would dramatically changes the T:E ratio.
The use of peptides by bodybuilders is still relatively new... so in an attempt to find out more about their applications and benefits I interviewed one of the premier research scientists at a lab responsible for their production.
In the weeks ahead I will examine many of these substances, but I thought I would start off with one of the most popular products on the market, the peptide known as Long R3 IGF-1 ...
Welcome to the first in a series where we take a closer look at steroids and peptides via an exclusive series of interviews with one of the head scientists at a major production laboratory.
First in line is Human Growth Hormone.....
So, first of all, why is Growth Hormone such an attractive drug to bodybuilders?
At first we tried "Cro-Mag," but it didn't roll well off the tongue. "Knuckle-dragger" and "Mr. Acromegaly" just seemed way too long. We finally settled on "Karloff" in honor of silver screen actor Boris Karloff, due to his classic portrayal of the Frankenstein monster.
Because the name was chosen as much for his caveman-like personality and lack of social graces as it was for his thick brow, jutting chin and prodigious use of growth hormone, the nickname (despite our every effort) wasn't taken as an insult. It stuck.
After spending the greater part of his life in bodybuilding, the anonymous subject of our interview stands at the critical juncture of his bodybuilding career. He has begun to compete at the National- level. This is a period in which many lifters "go for broke" and abandon logic for feats of daredevil chemistry, convinced that either their bodies are immune to harm or that ungodly dosages can overcome genetic limitations. Our subject is definitely more insightful than average. He has been around the sport in a variety of capacities, seen others climb fast and often go down in flames. He's aware of the realities of high-level competition but approaches things with thinking derived from observation and research, not insecurity.
On a recent episode of Super Human Radio I had the opportunity to interview Dr. Stephen Welle. Welle's group over at Rochester University of Medicine published a study that may be the single most important paper since the discovery of Myostatin by Dr. Se Jin Lee.
Many people have tried various OTC and pharmaceutical Myostatin inhibitors with little or no results. This has caused a general feeling that Myostatin inhibitors simply don't work. Well the problem may not be that these supplements and drugs are outright fakes, but instead, that the doses used are not achieving the required suppression levels.
Some of you have heard of the process to make Trenbolone acetate from cattle implant pellets (Finaplix), and have asked me how it is done. That number has risen to the point where I figured I'd tell you a little story about making one of my all-time favorite drugs yourself at home.
Deca Durabolin has a long history of use in the athletic community and remains, to this day, to be one of the most popular steroids in the sport's world. The popularity it enjoys stems from the fact that it has a very high anabolic activity and produces significant mass increases with relatively few side effects. It also produces less water retention, has less effect on blood pressure and is far less toxic to the liver and kidneys than most of its mass-building buddies.